Non-pacemaker cells are what type of response?

Prepare for the Cardiac Electrophysiology Test. Enhance your knowledge with flashcards and multiple-choice questions, each supplemented with explanations and hints. Gear up for success on your exam!

Multiple Choice

Non-pacemaker cells are what type of response?

Explanation:
Non-pacemaker cardiac cells, such as atrial and ventricular myocytes and Purkinje fibers, generate a fast-action-potential upstroke. This rapid depolarization is driven by the quick opening of voltage-gated Na+ channels, giving a steep phase 0 and high conduction velocity through the heart muscle. The resting membrane potential stays relatively stable, and after the fast upstroke, Ca2+ influx through L-type channels creates the characteristic plateau (phase 2) that supports contraction before repolarization. Pacemaker cells, by contrast, rely on a slower Ca2+-mediated upstroke and automatic phase-4 depolarization, which is why they’re described as slow-response. So non-pacemaker cells are fast-response.

Non-pacemaker cardiac cells, such as atrial and ventricular myocytes and Purkinje fibers, generate a fast-action-potential upstroke. This rapid depolarization is driven by the quick opening of voltage-gated Na+ channels, giving a steep phase 0 and high conduction velocity through the heart muscle. The resting membrane potential stays relatively stable, and after the fast upstroke, Ca2+ influx through L-type channels creates the characteristic plateau (phase 2) that supports contraction before repolarization. Pacemaker cells, by contrast, rely on a slower Ca2+-mediated upstroke and automatic phase-4 depolarization, which is why they’re described as slow-response. So non-pacemaker cells are fast-response.

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